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Wednesday, August 26, 2020
Budget Variance Report for Hospital Department Assignment
Spending Variance Report for Hospital Department - Assignment Example The specialist of this task talks about the accepted procedures, that are required when setting and overseeing wellbeing medical clinic spending plans. These essentially, incorporate yet not constrained to utilizing near benchmarks, setting exceptional, superior division spending plans, building up a social point of view of responsibility, overseeing costs, for example, pay rates and supplies agreeably, maintain observing changes and having restorative activity plan and utilizing a decent scorecard. In the same way as other wellbeing frameworks offices normally trail to achieve its activity focuses with this case nearby of variety of more significant compensations and considerably more than provisions noted. For that month, capacity to meet planned working edge targets was impractical. Subsequently, supplies had repressed expected normal month to month working edge to help the emergency clinic in running its area of expertise. To conclude that, the scientist of this task is to take a gander at factors that came about to the difference. During that time, the office burned through 80% more on things not planned for that month implied a 3.6% normal spending fluctuation. Notwithstanding, a basic look demonstrated that 40% of the 80% dollar esteem totaled essential spans added to surprising volume increment after the spending plan initially drawn. The specialist expresses that spending change report should have been made from general record framework, income and costs. Different elements considered in this task are genuine outcomes, spending fluctuation, percent change and alongside financial plan.
Saturday, August 22, 2020
Assignment 2 Essay Example | Topics and Well Written Essays - 750 words - 6
Task 2 - Essay Example The numerical model introduced by the Deming was viewed as unreasonable model. The new methodology of business introduced by Deming requested to change the entire framework and totally rebuild the framework. Rebuilding the total framework made the model disputable. Demingââ¬â¢s idea of variety can be executed to the homeroom by understanding the factual hypothesis. With the execution of the measurable hypothesis, it is anything but difficult to diminish the effect of variety by actualizing and improving innovation, plan of the examination and through legitimate preparing of staff and understudies. A wood cutting machine cuts wood signs into alluring estimated amble. Wood logs are physically embedded with the assistance of lifting machine and afterward the logs are cut into half and afterward equivalent measured equal pieces of timber are cut. The basic variety factors are hardness of the wood logs, wear of the cutting edges and machine vibrations. A few times the size of the wood logs contrasts from each other. In the comparable way, some of the time the cutting edge quits pivoting which is caused because of the mistake of the engine bearing. Deming gave an orderly and scientific quality control training strategy that necessary science, statics, and modern designing administration. There is a need to produce vision, instruct the understudies drew closer to be fruitful, choice ought not just founded on viable expense, continually improve the framework, train the staff and recruit individuals with great information and aptitudes to educate, give direction to the understudies as opposed to being their masters, gain regard of the understudies as opposed to requesting the regard, reward the endeavors of the understudies, never rebuff the understudies however permit than to self develop themselves. Juranââ¬â¢s theory underlines that quality, creation and economy can be expanded by improving the administration. He depicted the three administration improving plans to improve the systemââ¬â¢s
Tuesday, August 11, 2020
The Worst Christmas Ever
The Worst Christmas Ever Itâs Christmas Day. Little Andy tears off wrapping paper to reveal Optimus Prime. He smiles as the large robot toy comes to life with flashes and beeps. Andyâs parentsâ expressions, however, are more pained grimaces than smiles. A few minutes later, Andy discards the toy and begins unwrapping the rest of his presents, extracting each box from under the tree, one by oneâ"some long, some tall, some heavy, some light. Each box reveals a new toy; each shred of wrapping paper, a flash of happiness. An hour later, however, little Andy is crying hysterically. Based on his fits, this has undoubtedly been the Worst. Christmas. Ever. Sure, Andrew received many of the things on his listâ"but heâs far more concerned with what he didnât receive. The toys in front of him simply remind him of what he doesnât have. Sounds childish, but we do the same thing: we look at things around us and want more. We covet the neighborâs new car, the co-workerâs new clothes, the friendâs new iPhone. What if Andy was happy with the toys in front of him? What if we were, too? Subscribe to The Minimalists via email.
Saturday, May 23, 2020
Abigail Adams Chapter Guide Essay - 934 Words
Haley Young Dearest Friend: A Life of Abigail Adams Reading Journal Chapter 1: A Ministerââ¬â¢s Daughter * Abigail was born to Reverend William Smith and his wife Elizabeth in Weymouth parsonage in Massachusetts. * She has two sisters, Mary and Betsey. The main point of this chapter was to showcase the religious, family-oriented background that Abigail was raised in. It explains why she is so focused on her family and John later in her life. It also explains her penname ââ¬Å"Dianaâ⬠and her love for literature and being involved in politics, after being taught to read at a young age. Chapter 2: John * Abigail and John were married on October 25, 1764. The maim point of this chapter is to show the love developing between John andâ⬠¦show more contentâ⬠¦Chapter 8: The Long Separation * After his commission to France, John was elected minister plenipotentiary which extended his stay in Europe. Chapter 9: Years of Decision * While John was in Europe, Abigail couldnââ¬â¢t decide whether or not to join him, but when he was commissioned to negotiate a treaty of commerce with Great Britain, she and Nabby decided to go and join him in Europe. * Nabby fell in love with Royall Tyler so the trip was also to see if their love would last. Chapter 10: Europe * Abigail liked London because of the class but disliked Paris because she thought it was dirty and the people were rude. * The servants did less in Europe, so it was more expensive to run a household ,which frustrated Abigail. * John was then appointed minister to London by congress. Chapter 11: ââ¬Å"The Ambassadressâ⬠* Abigail was overwhelmed by the wealth of the royal court in London. * She and John were not used to the expenses of clothing, servants, and hosting dinners for other dignitaries. This was made even worse by the low salary John was being paid by Congress. Chapter 12: A Homesick American * In London, Abigail continued to miss American and her easy-going life in the countryside because she felt confined in the city in London. Chapter 13: The Vice Presidentââ¬â¢s Lady * After Europe,Show MoreRelated Importance of Early American Women Writers Essay2207 Words à |à 9 Pagessleep for writing gave women American writers their start (4). Different styles of writing emerged from various early American women writers in each century, there by setting a precedent for those that followed. Anne Bradstreet, Phillis Wheatley, Abigail Adams, Hannah Foster, Susanna Rowson, and Louisa May Alcott established new forms of literary styles like poetry, letters, fiction, and novels in the 17th, 18th, and 19th centuries. Anne Bradstreet established domestic tradition in American poetryRead MoreAmerican Revolution and Study Guide Essay example5377 Words à |à 22 PagesChapter 2 Study Guide Questions ââ¬Å"The Planting of English Americaâ⬠1. Discuss English treatment of the Irish and its consequence (10pts) 2. What lessons do you think English colonists learned from their early Jamestown experience? Focus on matters of fulfilling expectations, financial support, leadership skills, and relations with the Indians. What specific developments illustrate that the English living in the plantation colonies tried to apply these lessons? (25 pts) 2. Compare and contrastRead MoreSummary Of Thirty Years A Slave By William Wells Essay1513 Words à |à 7 Pagesindependence to guide the 13 colonies, stating ââ¬Å"We hold these truths to Bickes 2 be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable rights, that among these are Life, Liberty, and the pursuit of Happinessâ⬠(US 1776). The time to separate from the British Empire had arrived, but the Founding Fathers dismissed unlocking the chains of their poorly treated cooks, harvesters, and maids. Abigail Adams, wife of Founding Father John Adams, threatenedRead MoreApa Style Lite for College Papers15275 Words à |à 62 PagesAPA STYLE LITE FOR COLLEGE PAPERS American Psychological Association Style for Final Manuscripts by Dr Abel Scribe PhD - January 2010 APA Lite for College Papers is a concise guide to crafting research papers in the style of the American Psychological Association (APA). It is based on the current edition of the APA Publication Manual (corrected printing, 2009) while incorporating guidelines for ââ¬Å"Material Other Than Journal Articlesâ⬠found in the last edition. APA Lite succeeds the APA Crib SheetRead MoreDried Malunggay (Moringa Oleifera) Leaves in Ethanol Production6983 Words à |à 28 PagesNational High School Special Science Curriculum In Partial Fulfillment of the Requirements for Research I Proponents: Catangay, Jhantal A. Gicana, Emchie Elaine R. Marasigan, Jan Ian B. Natividad, Abigail Jacinthe B. Viaje, Kyrinne Kate M. Zara, Hazel Jane Muriel C. March 2012 CHAPTER 1 THE PROBLEM AND ITS BACKGROUND We all know that ethanol or ethyl alcohol has a very good contribution to our life. Ethyl alcohol is an important industrial chemical. It is used as a solvent, in the synthesisRead MoreTax Code6625 Words à |à 27 Pages CHAPTER 3 TAX DETERMINATION; PERSONAL AND DEPENDENCY EXEMPTIONS; AN OVERVIEW OF PROPERTY TRANSACTIONS SOLUTIONS TO PROBLEM MATERIALS | | | | |Status: | | Q/P | |Question/ | | | |Present | | in Prior | |Problem | |Topic Read MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words à |à 1573 PagesCommunication 353 Filtering 353 â⬠¢ Selective Perception 353 â⬠¢ Information Overload 353 â⬠¢ Emotions 353 â⬠¢ Language 354 â⬠¢ Silence 354 â⬠¢ Communication Apprehension 355 â⬠¢ Lying 355 Global Implications 356 Cultural Barriers 356 â⬠¢ Cultural Context 357 â⬠¢ A Cultural Guide 358 Summary and Implications for Managers 360 S A L S A L Self-Assessment Library Am I a Gossip? 336 An Ethical Choice The Ethics of Gossip at Work 345 Myth or Science? ââ¬Å"We Know What Makes Good Liars Goodâ⬠356 glOBalization! How DirectRead MoreLeading Function of Management15642 Words à |à 63 Pageswork workers. Motivation- means inspiring, stimulating or encouraging the sub-ordinates with zeal to work. Positive, negative, monetary, non-monetary incentives may be used for this purpose. Leadership- may be defined as a process by which manager guides and influences the work of subordinates in desired direction. Communications- is the process of passing information, experience, opinion etc from one person to another. It is a bridge of understanding. 5. Controlling It implies measurement of accomplishment
Tuesday, May 12, 2020
Narcissus Classic Greek Icon of Extreme Self-Love
Narcissus is a legendarily handsome young man in Greek mythology and the basis of a fertility myth. He experiences a particularly extreme form of self-love which leads to his death and transformation into a narcissus flower, fit to attract the goddess Persephone on her way to Hades.à Fast Facts: Narcissus, Greek Icon of Extreme Self-Love Alternate Names: Narkissus (Greek)Roman Equivalent: Narcissus (Roman)Culture/Country: Classical Greek and RomanRealms and Powers: The woodlands, no powers to speak ofParents: His mother was the nymph Liriope, his father the river god KephisosPrimary Sources: Ovid (The Metamorphosis III, 339ââ¬â510), Pausanius, Conon Narcissus in Greek Mythologyà According to Ovids Metamorphosis, Narcissus is the son of the river god Kephissos (Cephissus). He was conceived when Kephissos fell in love with and raped the nymph Leirope (or Liriope) of Thespiae, ensnaring her with his winding streams. Concerned for his future, Leirope consults the blind seer Tiresias, who tells her that her son will reach old age if he never knows himself, a warning and an ironic reversal of the classic Greek ideal, Know thyself, which was carved on the temple in Delphi.à Narcissus dies and is reborn as a plant, and that plant is associated with Persephone, who collects it on the way to the Underworld (Hades). She must spend six months of the year underground, which results in the changing season. Therefore, Narcissus tale, like that of the divine warrior Hyacinth, is also considered a fertility myth. Narcissus and Echo Although a stunningly beautiful young man, Narcissus is heartless. Regardless of the adoration of men, women, and mountain and water nymphs, he spurns them all. Narcissus history is tied up with the nymph Echo, who was cursed by Hera. Echo had distracted Hera by keeping up a constant flow of chatter while her sisters were dallying with Zeus. When Hera realized shed been tricked, she declared that the nymph would never be able to speak her own thoughts again, but could only repeat what others said.à One day, wandering in the forest, Echo meets Narcissus, who had been separated from his hunting companions. She tries to embrace him but he spurns her. He cries I would die before I would give you a chance at me, and she answers, Id give you a chance at me. Heartbroken, Echo wanders off into the forest and eventually mourns her life away to nothing. When her bones turn to stone, all thats left is her voice answering others lost in the wilderness. Echo and Narcissus, 1630, by Nicolas Poussin (1594-1665), oil on canvas. G. Dagli Orti / Getty Images A Fading Death Finally, one of Narcissus suitors prays to Nemesis, the goddess of retribution, imploring herà to make Narcissus suffer an unrequited love of his own. Narcissus reaches a fountain where the waters are unruffled, smooth and silvery, and he stares into the pool. He is instantly smitten, and eventually recognizes himselfââ¬âI am him! he criesââ¬âbut he cant tear himself away.à Like Echo, Narcissus simply fades away. Unable to move away from his image, he dies from exhaustion and unsatisfied desire. Mourned by the woodland nymphs, when they come to gather his body for burial they only find a flowerââ¬âthe narcissus, with a saffron-colored cup and white petals. To this day, Narcissus lives in the Underworld, transfixed and unable to move from his image in the River Styx.à White daffodils on a rustic wooden background. Marfffa / Getty Images Plus Narcissus as a Symbol To the Greeks, the narcissus flower is a symbol of early deathââ¬âit is the flower gathered by Persephone on her way to Hades, and it is thought to have a narcotic fragrance. In some versions, Narcissus is not transfixed by his image out of self-love, but instead mourns his twin sister. Today, Narcissus is the symbol used in modern psychology for a person afflicted with the insidious mental disorder of narcissism. Sources and Further Information Bergmann, Martin S. The Legend of Narcissus. American Imago 41.4 (1984): 389ââ¬â411.Brenkman, John. Narcissus in the Text. The Georgia Review 30.2 (1976): 293ââ¬â327.Hard, Robin. The Routledge Handbook of Greek Mythology. London: Routledge, 2003.Leeming, David. The Oxford Companion to World Mythology. Oxford UK: Oxford University Press, 2005.Smith, William, and G.E. Marindon, eds. Dictionary of Greek and Roman Biography and Mythology. London: John Murray, 1904.
Wednesday, May 6, 2020
Biography of Barack Obama Free Essays
string(57) " nationalist party of the revolutionary, radical Blacks\." Senator Barack Obama (D, Illinois) said that nowhere else is his ââ¬Å"story even possible. â⬠The junior senator is a candidate for his partyââ¬â¢s 2008 presidential nomination. Born Barrack Hussein Obama on August 4, 1961 in Honolulu, Hawaii to Barack, Sr. We will write a custom essay sample on Biography of Barack Obama or any similar topic only for you Order Now and Ann Dunham. Barack Sr. was a goat herder like his own father, a servant in the home of the British. The Obamas were from the Luo ethnic group of Nyanza Province in Kenya. Ann was a White American from Wichita, Kansas whose father was an oil rigger during the Depression. At the outbreak of World War II he enlisted in the army of General Patton. Her mother worked in the production line of bombers. At the end of the war, they pursued their studies through the G. I. Bill. With the Federal Housing Program they purchased their house and settled in Hawaii. In the 1950s, the Obamasââ¬â¢ Luo ethnic group was a frontrunner in Kenyaââ¬â¢s struggle for independence. The Dunhams, on the other hand, were against slavery as early as the 1800s. Barack Obamaââ¬â¢s parents met at the East-West Center, Manoa Campus of the University of Hawaii. Barackââ¬â¢s father was on a scholarship and was the first ever from a country in Africa. The marriage did not last, as interracial unions were not accepted. In some states it was illegal. It was not much of a problem to the Dunhams but it was to the Obamas, who found it difficult to have a White American for a daughter in law. Under the circumstances, they had to divorce when Barack was two years old. Barack Sr. moved to Harvard on another scholarship for a Doctorate in Economics. Father and son met again when Barack was ten. They kept in touch through letters until Barack Sr. ââ¬â¢s return to Kenya and his death by car accident in the early 1980s. Barackââ¬â¢s mother remarried. Lolo Soetoro, an Indonesian student of the East-West Center became her husband. In 1967 when Barack was six they moved to Jakarta where Lolo got a job in an oil company. Barackââ¬â¢s half-sister Maya was born. Barack went to school in Jakarta where lessons were conducted in Indonesian. Barack or Barry returned to Hawaii when he was 10. He joined his grandparents, Madelyn and Stanley Dunham. His mother lived with them later until her death in 1995 due to ovarian cancer. In 1979, Barack graduated with honors at the renowned Punahou Academy. They were only 3 Black students in Punahou. It was at this time that became conscious as well as concerned about mixed racial heritage. He was troubled about racism and his African-American background. He could not deal with his being African-American having a White American family. He turned to cocaine, marijuana and alcohol. Just like most teens of his background they needed an outlet for their inner rage and in the process tended to self-destruct. After Punahou, he transferred to Occidental College in Los Angeles where he got his act together. After two years he moved to the esteemed Columbia University in New York. He got to visit Kenya for the first time and renewed ties with his relatives. He graduated from Columbia with a Degree in Political Science. For a while he involved himself in community work in Harlem. He decided he could not live to support himself with so little pay. He decided to leave New York and move to Chicago. The South Side of Chicago is an impoverished community. Barack worked as a community organizer for the poor residents of Roseland and the development of public housing for Altgeid Gardens. Law school beckoned. This time his application was accepted by Harvard Law School, one of the best in the country. He became the first African-American president of the Harvard Law Review Journal. It opened doors of opportunities for him upon graduation. He graduated Magna Cum Laude in 1991. True enough, top Manhattan law firms came knocking on his door. $100,000 annual pay offers were turned down by Barack. He opted to return to Chicago to work for Miner, Barnhill Galland as a civil rights lawyer. He handled housing and labor discrimination cases, taught at the Law School of the University of Chicago and organized voter registration drives. The large turnout of registered Black voters in Chicago, helped bring Bill Clinton straight to the White House in 1992. Chicago has a special place in Obamaââ¬â¢s heart. In 1988 while working as a summer associate in Sidley Austin, a Chicago Law Firm, Michelle Robinson was assigned as his mentor. Michelle was also a graduate of Harvard Law School. She was from a Black, working-class family on the South Side. She and a brother who excelled in Basketball went to Princeton University. Michelle obtained her undergraduate degree at Princeton. Michelle became Mrs. Obama, when he married her in October 1992. They have two daughters, Malia and Sasha. Michelle and the girls have remained in Kenwood on Chicagoââ¬â¢s South Side instead of moving to Washington. Michelle still works as an executive in a hospital. In 1996 Barack Obama ran for and won a senate seat from Hyde Park, his home district. Hyde Park is the neighborhood around the University of Chicago. The community even with its upscale side has a high rate of crime and unemployment. Among Obamaââ¬â¢s accomplishments are: tax breaks for the low-incomed, a state insurance to include uninsured children, increase health care services as well as education programs in early childhood for the poor, and tracking stops and speed of drivers by law enforcers. The latter was supposed to reduce discriminatory profiling by police patrol officers. Another significant legislation was for police to videotape confessions on homicide cases. In 2000 he made a try for a congressional seat against Bobby Rush, a Black former member of the Chicago City Council. Rush was the founder of the Black Panther Party, Illinois Chapter. The Black Panther was the 1960s nationalist party of the revolutionary, radical Blacks. You read "Biography of Barack Obama" in category "Papers" Rush capitalized on his experience and criticized Obamaââ¬â¢s wealthy and white votes. Obama experienced his first major defeat garnering only 30% of the votes. In 2004 when Peter G. Fitzgerald (R, Illinois) bared plans of retirement, Obama made a bid for a senate seat. When supporters thought it premature for him to aim for a position that high, they were certainly in for a big surprise. Obama garnered 53% of the votes in the primary, against 6 other challengers. This appeared to be a record high among African-Americans who figured prominently in white-populated precincts. These made the Democrats take him and his campaign more seriously. In the 2004 senate elections, he faced Jack Ryan of the Republicans. Ryan was a good-looking parochial school teacher, who used to be an investment banker. His former wife was Jeri Ryan, the star of Boston Public. There were issues on the Ryansââ¬â¢ divorce that did not sit well with the Republicanââ¬â¢s platform with regards to family values. Jack Ryan withdrew from the race. Alan Keyes, the talk show host from Maryland moved to Illinois to oppose Obamaââ¬â¢s senate bid. Keyesââ¬â¢ adversarial stand on homosexuality and his two unsuccessful white house campaigns did not make him a strong opponent. With free trades that removed tariffs, US industries started to transfer their factories outside of the United States. Such meant great loss of jobs and employment. Obamaââ¬â¢s campaign promise was a halt in bringing jobs overseas. That swayed the votes for Obama. What would happen next would Obamaââ¬â¢s defining moment. In the Democratic National Convention of July 2004 Obama delivered the keynote address of the convention as requested by John Kerry who would end up the partyââ¬â¢s standard bearer. Much was expected of Obama and he delivered! He earned praises and standing ovations for his well-crafted speech and his eloquent delivery. He spoke about the need for America to unite in order that it may be strong. He reminded everyone of Americaââ¬â¢s diverse ethnicity and ideologies that made the county rich. He said that the American way was to provide for all, not for just a few. If there was an elderly who was not at all related to him and was too poor to pay both rent and medicines, Barack Obama said, it made his life poorer. He said the people should mind what injustice is committed to his fellowmen like a brother to a brother. He believed that such acts of concern make America work. Analysts found in Obamaââ¬â¢s speech a great amount of positivism, hope and optimism. They all found a promise in Obama, an emerging leader among the Democrats and possibly a near-future president of America. 70% of the votes of Illinois went to the 43 year old Obama with only 27% left for Keyes in the senatorial contest. In the US Senate of 2005, Obama was one of the youngest. His first significant legislation was the Higher Education Opportunity through the Pell Grant Expansion Act of 2005 or the HOPE Act. This was for those students who received financial aid for college from the Federal Government, the legislation aimed for an increase in the amount provided. He crossed party lines to seek support for important legislations. He teamed up with Sen. Richard Lugar (R, Indiana) for a bill to expand efforts to destroy all weapons of mass destruction in Russia and Eastern Europe. Together with Sen. Tom Corburn (R, Oklahoma) they kept tight watch on government spending through a website they created. He and Sen. Russ Feingold (D, Wisconsin) also sought to stop the lobbyists from giving members of Congress gifts like travel on private jets. He raised vital issues on the senate floor like awareness of Avian flu and its threats, the destruction of Hurricane Katrina and its victims, alternative fuel sources and worked for better benefits for the veterans. As senator he is on the Health, Education, Labor and Pensions Committee, the Foreign Relations Committee, the Veterans Affairs Committee and the Environment and Public Affairs Committee. In US history, Obama is the fifth African American elected to the senate in 2005 and only the third towards the end of Reconstruction. Obama joined the few other Blacks who made it to the senate, the first ever was Hiram Rhoades Revels of North Carolina in 1870, Blanche K. Bruce of Virginia in 1875, Edward William Brooke III from Massachusetts in 1966, and Carol Moseley Braun from Illinois in 1992. Braun is also the first African-American woman elected to the senate. Obama was a strong critic of President Bushââ¬â¢ policy on Iraq since the 9/11 terrorist attacks. He spoke against using force in Iraq at the Chicagoââ¬â¢s Federal Plaza rally of October 2002. Barack Obama opposed what he called ââ¬Å"dumb warsâ⬠and was particularly concerned with the lives they had cost. He believed that there was a better way to handle Saddam Hussein. He saw Iraqââ¬â¢s economy battered and his military weak and that there was no way for Saddam but down. He knew that the war in Iraq will be a protracted one with an unpredictable end, costs, and consequences. He warned that it could bring out the worst from the Middle East, the Arab world and the Al-Qaeda. He has authored two books, namely: (1) His autobiography ââ¬Å"Dreams from My Father: A Story of Race and Inheritanceâ⬠published in 1995, and (2) ââ¬Å"The Audacity of Hope: Thoughts on Reclaiming the American Dream,â⬠published in 2008. Obama announced that he is gunning for the 2008 Democratic presidential nomination. He is up against the Sen. Hillary Rodham-Clinton. Works Cited ââ¬Å"About Barack Obama. â⬠2008. United States Senate. 6 May 2008 http://obama. senate. gov/about/ ââ¬Å"Barack Obama Biography. â⬠2006. Thomson Gale, a part of the Thomson Corporation. 6 May 2008 http://www. notablebiographies. com/news/Li-Ou/Obama-Barack. html ââ¬Å"Barack Obama Biography (1961-)â⬠2008. bio. biographies. com. 6 May 2008 http://www. biography. com/search/article. do? id=12782369page=1 ââ¬Å"Meet Barack. â⬠2008. Barack ââ¬â¢08. BarackObama. com. 6 May 2008 http://www. barackobama. com/about/ How to cite Biography of Barack Obama, Papers
Sunday, May 3, 2020
Melanoma Antigens And Antibodies Springer â⬠Myassignmenthelp.Com
Question: Discuss About The Melanoma Antigens And Antibodies Springer? Answer: Introduction Melanoma is defined as the most dangerous form of skin cancer (ReisfeldFerrone, 2012).The World Health Organization (WHO) estimates that worldwide there are 66,000 deaths annually from skin cancer, with approximately 80% due to melanoma(Hodi et al., 2010, pp. 712).The main cause behind the occurrence of melanoma is the ultra violet radation causing damage of the DNA of the skin cells or in the pigment producing melanocytes, to be precise(RassReichrath, 2008, pp. 162-178). This damage is manifested as detrimental DNA mutation leading to the development of the malignant tumors or melanoma(RassReichrath, 2008, pp. 162-178). The other causes of melanoma apart from increased sun exposure or exposure to ultraviolet (UV) radiation are, increased in the rate of outdoor activities, a total change in the dressing style, increased rate of longevity, high rate of ozone layer depletion or global warming, geneticpredispositionand immune suppression(LeiterGarbe, 2008, pp.88-103). The tumours origin ate in the basal layers of the epidermis and mostly resembles to skin moles during the initial stage of the development(Shields et al., 2011, pp. 389-395). Melanoma is curable if detected and treated early. However, in the majority of the cases, melanoma remains undetected during its latent stage and leading to the principal cause of death behind skin cancer (Tsao et al., 2015, pp.717-723). The following report will shed a detailed light on the prevalence of melanoma in Australia and Japan. The report also discusses three possible treatments for curing melanoma and the role of the healthcare professionals in providing such treatments. At the end, the report throws a brief light on the impact of this fatal disease, melanoma on the community. Prevalence of Melanoma in Australia Australia has one of the highest occurancerates of melanoma in the world (Melanoma Institute Australia, 2017). The occurrence rate is so high that melenoma is now regarded as Australias national cancer. It is the third most common cancer in Australia. Melanoma comes only after prostate cancer (male)/breast cancer (female) and bowel cancer(Melanoma Institute Australia, 2017). Parameter Percentage of Occurrence Year Occurrence rate in male 12% of all cancer 2017 Occurrence rate in female 9% of all cancer 2017 Total population diagnosed 14000 2017 Rate among skin cancer 2% 2017 Casualty of melanoma 75% of all skin cancer death 2017 Table: Prevalence Rate of Melanoma in Australia Prevalence of Melanoma in Japan According to the nationwide survey with malignant skin tumours conducted among the Japanese patients during the year of 1987 to 2001 reflected that basal cell carcinoma is the most prominent cancer in Japan followed by squamous cell carcinoma and malignant melanoma(Ishihara, Saida, Otsuka Yamazaki, 2008, pp.33-41). Malignant melanomas are mostly observed in the skin and are rare in the mucosal region of head and neck(Shiga et al., 2012). The male to female ratio was found to be 1: 0.97 to 1: 1.14(Ishihara, Saida, Otsuka Yamazaki, 2008, pp.33-41). The survival rate has found higher in females than that of male (70.6% female and 60% male)(Ishihara, Saida, Otsuka Yamazaki, 2008, pp.33-41). As per the age distribution, melanoma is detected during the later stages in life during 40 to 49 years of age with highest occurrence rate at the age of 60 years(Ishihara, Saida, Otsuka Yamazaki, 2008, pp.33-41). Sole of the foot was found as the main site of occurrence for melanoma in both males and females. However, lower limbs of the females were also detected as the common site of occurrence. Among Melanoma type, AcralLentiginous melanoma accounted to about 50% of occurrence among the Japanese population which is followed by nodal melanoma (Ishihara, Saida, Otsuka Yamazaki, 2008, pp.33-41). Treatment for Melanoma Adjuvant therapy with interferon alpha is the best suited therapy for the patients who are suffering from surgically restricted melanoma without or without the metastases of the lymph node. Interferon alpha is the principal agent to deliver significant survival benefit in patients who are suffering from high risk melanoma(Garbe, Eigentler, Keilholz, Hauschild Kirkwood, 2011, pp. 5-6). According to Garbe et al., (2011), patient patients who received intravenous therapy for interferon alpha 2b (20 million units per meter square per day) for one month showed increases rate of survival. This dosage instruction was further revised with 10 million units per meter square, 3 times per week for tenure of 48 weeks(Garbe et al., 2011). Chemotherapy Chemotherapy is by far the most accepted palliative therapy for melanoma. It is used for the treatment of stage four metastatic melanoma. Among the chemo therapeutic agent, the most popularly used drug for the treatment of melanoma is decarbazine(Garbe, Eigentler, Keilholz, Hauschild Kirkwood, 2011, pp.10). On the other hand, oral consumption of temozolomide and yield same success result in comparison to that of decarbazine(Garbe, Eigentler, Keilholz, Hauschild Kirkwood, 2011, pp. 10).The antitumor activity of decarbazine is not because of the formation of diazoniumcations but due to the subsequent high proteolysis rate of decarbazine(Iradyan, Iradyan, Stepanyan, ArsenyanGaribdzhanyan, 2010, pp. 175-176). As per the obswervation, administration of decarbazine results in the oxidation of the long triazene chain present in the microsomonal cells of the human body. This leads to cell death in the G1 phase of the cell cycle. Sometimes, cell death is also encountered in early S-phase of t he mitosis cell cycle (Iradyan, Iradyan, Stepanyan, ArsenyanGaribdzhanyan, 2010, pp. 175-176). Immunotherapy This therapy is recommended for the immuno suppressed individuals who are suffering from melanoma. The immunotherapy has been found to improve the process of immune recognition followed by antitumor immune response of the effector via the process of antigen presentation and eliciting effector memory T-cells(Garbe, Eigentler, Keilholz, Hauschild Kirkwood, 2011 pp. 9). This therapy is also known as vaccination therapy and is found to be effective at it prevents recurrence of the disease due to the generation of the memory response. The advanced in the domain of structural analysis of the antigenic epitiopes have led to the foundation of the immunotherapy (Garbe, Eigentler, Keilholz, Hauschild Kirkwood, 2011 pp. 9). Role of Health Professionals Providing the Treatment Apart from framing proper treatment regime for the patient there are other important roles that need to be played by an oncologist. Communication related the overall disease prognosis, treatment and advanced therapy plan to the patient and the family is one of the vital parameters in the domain of developing a strong relationship between the oncologist and the patient(Fujimori, Shirai, Asai, Kubota, Katsumata Uchitomi, 2014).. Proper communication and development of trust helps the patient to generate less psychological stress and promoting quality of life and well-being during the treatment(Fujimori, Shirai, Asai, Kubota, Katsumata Uchitomi, 2014).. One of the greatest challenges for the oncologist is, breaking the bad news in the front of the patient and his family members. Questions related to the disease prognosis, the life expectancy of the patient needs to be answered with care and in detail. This is indeed a stressful task and demands a lot of knowledge in the field of signs o f the disease prognosis and proper flexibility in the communication skills with the patients and sensitivity(Fujimori, Shirai, Asai, Kubota, Katsumata Uchitomi, 2014). Apart from administering medicines, the oncologist needs to be careful about the nutritional balance of the patient. Since chemotherapy causes high level of immune suppression(Kudo-Saito, Shirako, Takeuchi Kawakami, 2009, pp. 195-206), proper nutritional back is mandatory for maintain the patient physical health strong enough to withstand the overall therapy. Oncology Nurse Oncology nurses practise in diverse settings. The settings encompass, acute care unit of the hospital, ambulatory care clinics in the hospitals, radiation therapy unit and as an assistant with the private oncologist(Swanson Koch, 2010).Nurses in the oncology unit are expected to be nimble in assessing both the physical and emotional status of the patient. This is usually done via knowing patients past history. They also review the treatment plan with the oncologist and are totally aware of the possible outcome of the disease treatment(Swanson Koch, 2010). The nursing care plan for a patient with melanoma is framed in response to the specific needs of the patient like patients understanding of the disease via educating them, setting proper therapy goals, psychological and physical preparation of the patient and compliance(Corner Bailey, 2009). Impact on Community Melanoma has a huge impact on the community. It affects the social and emotional well-being of the patients who are suffering from melanoma and these affects are gradually imposed on the care givers and the members of the family(Cancer Institute NSW, 2017). The common emotional reaction to cancer like melanoma are anger or sadness, fear or feeling out of control or feeling that there is nothing that they can do to save themselves from this fatal disease(Cancer Institute NSW, 2017). The social and emotional issues are extremely difficult for the patients to understand or to discuss about. This can also lead to problem like severe mental depression and anxiety(Cancer Institute NSW, 2017). Conclusion Thus from the above discussion it can be concluded that melanoma most dangerous form of skin cancer with highest prevalence rate in Australia and Japan. Melanoma or skin cancer is however canbe effectively treated if detected at an early stage of disease prognosis. Three of the most commonly used therapy for the treatment of melanoma is adjuvant based drug therapy via interferon alpha, chemotherapy and immunization therapy. Of these three therapies, chemotherapy is the most widely accepted therapy in the treatment of melanoma. It is generally recommended when there is no chance or scope for operation or surgery. Two of the most important pillars of the health care professionals in the treatment of melanoma are oncologist and a registered nurse in the domain of oncology. However, in spite of the high possibility of getting cured and advancement in the field of cost effective treatment and medical research, cancerous disease like melanoma affects the social and the emotional well-being of the affected person. References Corner, J., Bailey, C. D. (Eds.). (2009).Cancer nursing: care in context. John Wiley Sons. Fujimori, M., Shirai, Y., Asai, M., Kubota, K., Katsumata, N., Uchitomi, Y. (2014). Effect of communication skills training program for oncologists based on patient preferences for communication when receiving bad news: a randomized controlled trial.Journal of clinical oncology,vol. 32(20), pp. 2166-2172.DIO: 10.1200/JCO.2013.51.2756 Garbe, C., Eigentler, T. K., Keilholz, U., Hauschild, A., Kirkwood, J. 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